| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Magnesium Technology 2025
|
| Presentation Title |
The influence of porosity on the in vitro corrosion performance and biocompatibility of sintered WE43 and Mg-5Ca alloys |
| Author(s) |
Tom McKenna, Mert Celikin, Eoin O'Cearbhaill, Fiona Freeman |
| On-Site Speaker (Planned) |
Tom McKenna |
| Abstract Scope |
Magnesium-based alloys offer low cytotoxicity and elastic moduli as well as high specific strength, making them promising candidates for resorbable implant applications. However, porous defects are likely in most manufacturing processes, particularly in casting and in additive-manufacturing processes. This work examines the impact of porosity on the in vitro corrosion performance and biocompatibility of two partially-sintered alloys, WE43 and Mg-5Ca (5 wt.% calcium). Through variation of sintering temperatures and dwell times, partially-sintered samples — with different degrees of porosity — were rendered. Static immersion testing, potentiodynamic polarisation testing and electrochemical impedance spectroscopy were employed to characterise the corrosion behaviour of the samples. In vitro cell viability testing of sample extracts were performed using the MTT assay and MG-63 osteoblast-like cells. This work could pave the way forward for the future adoption of magnesium-based, resorbable implants. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Magnesium, Biomaterials, Other |