| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Magnesium Technology 2025
|
| Presentation Title |
Microstructure, mechanical properties, bio-corrosion behaviors and cytotoxicity of Mg-Zn alloy as bone fixation implant |
| Author(s) |
Kun Yu |
| On-Site Speaker (Planned) |
Kun Yu |
| Abstract Scope |
In the repair of bone defects, magnesium alloys have gained great attention as biodegradable materials for stent applications. However, high degradation rate cannot well match tissue repair process and may result in severe cytotoxicity. Control of the corrosion that occurs in magnesium alloys in vivo is a significant challenge for their use as resorbable orthopedic implants. The preparation of Mg-3%Zn, Mg-3%Zn-1%Y, WE43(Mg-2.5%Y-2.5%Nd) and Mg-2%Zn-1%Zr by casting extrusion method that can delay substrate corrosion while offering an attendant metal ions with properties known to promote an osteoinductive response in vivo. The mechanical properties and in vitro corrosion behavior of four kinds of alloys are studied the influence of material implantation on bone regeneration in the body and bone defect area. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Magnesium, Biomaterials, Mechanical Properties |