| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Society for Biomaterials: Biomaterial Applications
|
| Presentation Title |
Biodegradable Magnesium Fixation Wires for Bone Healing |
| Author(s) |
Karel Tesar, Anezka Jancova, Margit Žaloudková, Radka Vrbova, Martin Bartoš, Štefan Juhás, Jitka Lunackova, Karel Balík |
| On-Site Speaker (Planned) |
Karel Tesar |
| Abstract Scope |
This work will present the Mg-Zn fixation strands in the current stage of development as well as will discuss the initial in-vivo tests on pig sternum and other techniques. This solution can drastically reduce secondary surgeries that are sometimes needed for stainless steel wires due to nickel hypersensitivity and other possible conditions. This technology would be especially beneficial for pediatric and neonatal patients, where the growth is another factor for the usage of resorbable bone fixation. Presented magnesium-based fixation wires and strands dissolve completely in the body environment. To further improve the wire surface and to provide a drug carrier platform, individual wires are coated with a layer of a biodegradable copolymer. These coated wires are subsequently made into strands or bands. This approach utilizes the beneficial microstructure as well as prevents catastrophic failure of the whole implant if a single wire is defective or externally damaged. |