About this Abstract |
Meeting |
MS&T22: Materials Science & Technology
|
Symposium
|
Society for Biomaterials: Biomaterial Applications
|
Presentation Title |
Magnesium-Based Nanocomposites for Bone Fracture Repair |
Author(s) |
Shelby L. Hash, Mary Jia, Wendy Reynoso-Diaz, Mostafa Elsaadany, Hamdy Ibrahim |
On-Site Speaker (Planned) |
Hamdy Ibrahim |
Abstract Scope |
Over the last few decades, biodegradable orthopedic implants have been explored for human applications to address the problems of the currently-in-use permanent implants. Biodegradable magnesium offers a promising alternative due to its superior biocompatibility and advantageous properties compared to other biodegradable materials. However, magnesium has insufficient strength and it corrodes very quickly in body fluid, leading to poor biomechanical performance. One of the approaches to address these limitations is to reinforce magnesium with nanoparticles, to create magnesium-based nanocomposites, in hopes of improving its mechanical and corrosion properties. In this work, magnesium nanocomposites reinforced with different types and contents of nanoparticles were studied. A combination of powder metallurgy, hybrid sintering, and hot extrusion manufacturing processes was used to produce the nanocomposite parts. A significant enhancement in the hardness was achieved and the in vitro corrosion and cytotoxicity tests showed high levels of biocompatibility in terms of low cytotoxicity and degradation rates. |