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Meeting MS&T22: Materials Science & Technology
Symposium Society for Biomaterials: Biomaterial Applications
Presentation Title Magnesium-Based Nanocomposites for Bone Fracture Repair
Author(s) Shelby L. Hash, Mary Jia, Wendy Reynoso-Diaz, Mostafa Elsaadany, Hamdy Ibrahim
On-Site Speaker (Planned) Hamdy Ibrahim
Abstract Scope Over the last few decades, biodegradable orthopedic implants have been explored for human applications to address the problems of the currently-in-use permanent implants. Biodegradable magnesium offers a promising alternative due to its superior biocompatibility and advantageous properties compared to other biodegradable materials. However, magnesium has insufficient strength and it corrodes very quickly in body fluid, leading to poor biomechanical performance. One of the approaches to address these limitations is to reinforce magnesium with nanoparticles, to create magnesium-based nanocomposites, in hopes of improving its mechanical and corrosion properties. In this work, magnesium nanocomposites reinforced with different types and contents of nanoparticles were studied. A combination of powder metallurgy, hybrid sintering, and hot extrusion manufacturing processes was used to produce the nanocomposite parts. A significant enhancement in the hardness was achieved and the in vitro corrosion and cytotoxicity tests showed high levels of biocompatibility in terms of low cytotoxicity and degradation rates.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Additive Manufacturing and Characterization of Stimuli-Responsive Biomaterials for Cardiovascular Stents
Altering the Size of Doxorubicin Loaded DOPE:DOPC Liposomes to Target Cancer-Associated Fibroblasts and Utilizing Size-dependent Selective Targeting
Antimicrobial Biomaterials Target Intracellular Infection
Bioactive Glass and Its Role in Healing
Bioactive Polyelectrolyte Layer by Layer Assembled Corrosion Resistant Coatings on Surface Treated MgAZ31 Alloys
Biodegradable Ceramic Coating on Lithium-Aluminum-Zinc (LAZ) and Lithium- Zinc (LZ) Magnesium Alloys Using Micro-arc Oxidation
Biodegradable Magnesium Fixation Wires for Bone Healing
Combinatorial Approaches to Blood Contacting Materials
Development of a Microfluidic Blood-Vessel-on-Chip Model
Development of Natural Polymer-based Hydrogels for Corneal Tissue Engineering Applications
Development of Tissue-Specific, Perfusable Vasculature in Microphysiological Systems
Electrospraying Chitosan on Co-electrospun PCL/PVA Composite with Mesoporous Silica Particles to Release Curcumin for Skin Tissue Engineering Application
Exploring Single Electrospun PLGA Fiber Mechanics and Fiber Mat Applications in Cardiac Bioengineering
Exploring the Potential of Strontium Substituted Amorphous Calcium Phosphate and Dicalcium Phosphate Dihydrate Based Hydroxyapatite Forming Bone Cement
Harnessing Biological Functions in Dental Materials
Harnessing Perfluorocarbons to Enhance Oxygenation in Engineered Tissues
Hybrid 3D Bioprinting of Tissue Engineering Scaffolds with Dual Delivery Capability for Anticancer Drugs
Hydroxyapatite Loaded with 2-heptylcyclopropane-1-carboxylic Acid Inhibits S. Aureus Biofilm Formation
In Vitro Biochemical Analysis of Bioactive Glass Ionomer Cement (45S5) with Citric Acid as Setting Modifier
Magnesium-Based Nanocomposites for Bone Fracture Repair
Novel Biodegradable Porous Magnesium Alloy Scaffolds for Critical Sized Calvarial Bone Defect Reconstruction
Plant Polymer for Climate and Health Management
Platinum Wire-based Aptasensors Exploiting Self-assembled Monolayer (SAM) Components for Cardiac Biomarker Detection
Silanized Titanium for Delivery of Hydrophobic Therapeutic in Aqueous Environment
Silver Doped Titanium Oxide Layers for Improved Photocatalytic Activity and Potential Antibacterial Properties of Titanium Implants
Three-dimensional (3D) Iron Oxide Nanoparticles via Green Synthesis: A Review on Their Synthesis and Antibacterial Application
Utilizing Thiolyne Click Chemistry to Target Cancer Cells Using Folate Conjugated Liposomes

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