| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
2D Materials – Preparation, Properties, Modeling & Applications
|
| Presentation Title |
Graphene as a Bioscaffold for Musculoskeletal Tissue Engineering |
| Author(s) |
Dave Estrada |
| On-Site Speaker (Planned) |
Dave Estrada |
| Abstract Scope |
The intersection of graphene and biology has emerged as a promising nexus, where graphene’s physical properties may elucidate fundamental insights into biophysical, biochemical, and physiological mechanisms affecting behavior at the cellular, tissue, and system levels. However, graphene’s structure and properties are tightly coupled to synthesis and processing conditions, thus influencing biomolecular interactions at graphene – cell interfaces. In this talk, we review our recent progress in musculoskeletal tissue growth on graphene and graphene foam bioscaffolds with varying structure – property – processing – performance (SP3) correlations. We find that such SP3 correlations significantly influence musculoskeletal tissue formation, and gene expression, suggesting that the cell – graphene interface can be engineered to control biomolecule structure and function in adherent cells. We also highlight our recent progress in using graphene and MXene’s for other biomedical related applications. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Nanotechnology, Mechanical Properties |