| About this Abstract |
| Meeting |
MS&T23: Materials Science & Technology
|
| Symposium
|
3D Printing of Biomaterials and Devices
|
| Presentation Title |
C-1: 3D Bioprinting for Ophthalmic Applications |
| Author(s) |
Peter A. Jansen, Mia Jeter, Vedshree Deshmukh, Cynthia J. Roberts, Katelyn E. Swindle-Reilly |
| On-Site Speaker (Planned) |
Peter A. Jansen |
| Abstract Scope |
The creation of tissue engineered scaffolds through 3D bioprinting has become a more widely used process. In the field of ophthalmology 3D bioprinting of synthetic corneal replacements has gained considerable interest, in part due to the significant corneal donor shortage worldwide. Using extrusion 3D bioprinting allows for the manufacturing of synthetic corneal grafts. We are targeting desired material properties by varying printing parameters and base materials. The use of cellular and non-cellular materials is possible, and depending on the base materials these can be crosslinked during the printing process. To address immunologically challenged applications we are working to produce an acellular graft with low toxicity, which can be transplanted and would fully integrate with the surrounding tissue over time. We will show that naturally derived extrudable materials like silk fibroin, or gelatin can be used in the 3D extrusion bioprinting process to create viable biomaterial scaffolds. |