| About this Abstract |
| Meeting |
MS&T23: Materials Science & Technology
|
| Symposium
|
3D Printing of Biomaterials and Devices
|
| Presentation Title |
C-5: Release of Natural Medicines from 3D Printed CaP for Bone Tissue Engineering Applications |
| Author(s) |
Priya Kushram, Susmita Bose |
| On-Site Speaker (Planned) |
Priya Kushram |
| Abstract Scope |
Tumor ablation, osteoporosis, and osteomyelitis are all causes of critical-size bone defects that do not heal on their own. This reinforces the need for bone graft material that can repair these defects. 3D printing of calcium phosphate (CaP) scaffolds loaded with natural medicines provides a novel strategy to treat patient-specific defects, facilitating faster bone regeneration. Quercetin, a flavonoid found in onion, is known to show bone-forming abilities. Curcumin and allicin are biomolecules from turmeric and garlic extracts, also known to show therapeutic effects on bone. This work aims to show the effect of different natural medicines released from 3D-printed scaffolds on bone formation. Our studies show that quercetin enhances osteoblast cell viability by 1.3-fold and garlic extract increases by 1.2-fold compared to untreated samples. These results indicate that these multifunctional 3D-printed scaffolds loaded with natural medicines could be a promising strategy for bone tissue engineering applications. |
| Keywords |
Additive Manufacturing, |