| About this Abstract |
| Meeting |
MS&T23: Materials Science & Technology
|
| Symposium
|
3D Printing of Biomaterials and Devices
|
| Presentation Title |
3D Printed Biodegradable Polyester Scaffolds that Address Wound Biofilms and Bacterial Colonization |
| Author(s) |
Abraham Joy, Deliris Ortiz |
| On-Site Speaker (Planned) |
Abraham Joy |
| Abstract Scope |
We have developed a platform of 3D printable polyesters that are biodegradable within the timeframe of wound healing. Such polyesters can be encapsulated with therapeutics and 3D printed to provide bioactive scaffolds that address the physical and biochemical requirements for wound healing. In this talk we will present the design of polyesters designed for direct-write extrusion-based 3D printing and their fabrication into 3D printed scaffolds. We will also describe the design of polyurethanes and their antibiofilm properties. Encapsulation and release of the antibiofilm polyurethane, combined with an antibiotic enables disruption of the biofilm and decrease of bacterial load, enabling wound healing progression. This platform is envisioned to promote a pro-healing environment and recapitulate native wound healing while providing a cost-effective and widely deployable alternative to current devices in the clinic. |