About this Abstract |
Meeting |
MS&T23: Materials Science & Technology
|
Symposium
|
3D Printing of Biomaterials and Devices
|
Presentation Title |
Multifunctional Peptide Design for Functional Biomaterials |
Author(s) |
Candan Tamerler |
On-Site Speaker (Planned) |
Candan Tamerler |
Abstract Scope |
Peptides offer to design hybrid biomaterials that can mimic the functions of proteins, generate biomimetic platforms and modulate microenvironment. Clinically translatable biomimetic and bioactive materials integrated by peptide and peptide hybrids have the ability to present structural and functional diversity. Our group has been exploring peptide design from single to multi-functional domains to expand their bioactivity and harness engineered peptides in different applications. By merging experimental and ML integrated computational approaches, we design and enhance targeted properties of synthetic and protein derived short peptides for targeted functionality. Our approach combines the self-assembly with bioactivity to target biological target as well as offer modulation of the environment. In this presentation, we will summarize our recent studies including designing modular biomimetic platforms from imaging to ex vivo tissue repair and peptide-polymer adhesives for treating carious lesions. Overall, peptide engineering and peptide hybrid approaches represent the functional frontiers to mimic biological systems. |