| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials for Biomedical Implants
|
| Presentation Title |
Manipulating Precipitate Population to Modulate Corrosion and Al Release in Mg-9Al Biodegradable Implants |
| Author(s) |
Sreenivas Raguraman, Weilue He, Suhas Prameela, Tram Nguyen, Roger Guillory, Timothy Weihs |
| On-Site Speaker (Planned) |
Sreenivas Raguraman |
| Abstract Scope |
Magnesium alloys offer a promising alternative to traditional implant materials thanks to their biodegradability, biocompatibility, and excellent mechanical properties. Mg-Al alloys are one of the many alloy systems being considered for fabricating biodegradable implants. However, local and systemic biological accumulation and trafficking of Al eluted from Mg-Al alloys have not been studied in great detail. This study investigates the influence of tuning precipitate population on corrosion behavior, and Al-ions release into the bloodstream for a binary Mg-9Al alloy. Precipitate distribution was controlled through solution treatment, hot-rolling, and annealing, while degradation behavior was examined through in-vitro and in-vivo (subcutaneous implantation in mice) studies. A comprehensive range of characterization techniques, including SEM, XRD, Micro-CT, ICP, and TEM, were employed to analyze the structural changes pre-and post-corrosion. Our findings reveal that the precipitate population significantly affects the corrosion rate, mechanical properties, and release of Al ions. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Magnesium, Characterization, Biomaterials |