About this Abstract |
Meeting |
MS&T21: Materials Science & Technology
|
Symposium
|
Next Generation Biomaterials
|
Presentation Title |
4D Printed Shape Morphing PDLLA-co-TMC/GelMA Scaffolds for Tissue Regeneration |
Author(s) |
Xiaodie Chen, Jiahui Lai, Min Wang |
On-Site Speaker (Planned) |
Min Wang |
Abstract Scope |
4D printed tissue engineering scaffolds with shape morphing ability are very useful for the regeneration of many body tissues. Currently, shape memory polymers are commonly used materials for 4D printing in tissue engineering. But these materials are mostly synthetic polymers that do not provide good substrates for cell spreading and adhesion. Combining a synthetic shape memory polymer with a natural hydrogel (with excellent biocompatibility) is an effective way to obtain a polymeric material with both desired shape memory ability and good biocompatibility for 4D printing. In this study, shape morphing scaffolds with good biocompatibility were fabricated via 4D printing of polymer blends, which were composed of shape memory PDLLA-co-TMC and natural hydrogel GelMA (at 1:1, 2:1 and 3:1 blend ratios). The addition of GelMA in PDLLA-co-TMC improved the printability, stretchability and biocompatibility of the material while shape morphing ability was maintained. The blend ratio was found to affect these properties. |