Abstract Scope |
Recent advancements in nanotechnology have led to ground-breaking graphene-based nanofibers that promise to revolutionise healthcare. This study focuses on the biomedical applications of the nanofibers, synthesized using electrospinning and pressurized spinning techniques, incorporating graphene oxide (GO), graphene foam (GF), and porous graphene (PG). Notably, our research primarily focuses on the biomedical application of these nanofibers in three principle applications: antimicrobial treatments, self-powered biosensing, and vascular stent coating. The antimicrobial properties were extensively tested against a range of pathogens, including Phi6 Bacteriophage, Candida Albicans, and E. coli, demonstrating significant efficacy. Also, we have developed a triboelectric nanogenerator (TENG)-based biosensor using graphene derivatives and electrically conductive polymer (e.g. Polypyrrole), capable of electrochemically detecting glucose without external power. Lastly, the use of core-sheath graphene-based nanofibers allows for controlled drug release for vascular stent coating and presents an efficient nanodelivery system. This multifunctional approach underlines the potential of graphene/polymer-based materials in advancing medical devices. |