|About this Abstract
||2020 TMS Annual Meeting & Exhibition
||Recent Developments in Biological, Structural and Functional Thin Films and Coatings
||Antibacterial Effects of Photocatalytically Activated ZnO Nanoparticle Hydrogel Coatings
||Carol Mary Cleetus, Gisel M Fregoso, Mauro J Ruiz, Juan C Noveron, Binata Joddar
|On-Site Speaker (Planned)
The adequate coverage of wounds is often a challenge particularly when there is limited availability of healthy donor skin to harvest. The idea of a 3D printed customized wound-healing coating, which can be designed readily and made to fit the exact size and depth of the wound is, therefore attractive. An extrusion 3D bioprinter was used for printing of such a wound healing template using Alginate, a hydrogel and cross-linked with divalent Ca2+ ions. Zinc Oxide (ZnO) nanoparticles which are photocatalytic enabling them to release powerful hydroxyl (-OH) radicals for termination of harmful pathogens and bacteria in the wound site were also included. Addition of ZnO nanoparticles to the alginate pre-gel solution enhanced its shear-thinning properties as well as printability and extrusion. Since the alginate-ZnO scaffold is biocompatible and completely biodegradable in vivo, this phenomenon makes this particular concept more patient-friendly and marketable.
||Planned: Supplemental Proceedings volume