About this Abstract |
Meeting |
2020 TMS Annual Meeting & Exhibition
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Symposium
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Recent Developments in Biological, Structural and Functional Thin Films and Coatings
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Presentation Title |
Sono-electrodeposition Approach for Biomimetic Calcium-deficient Hydroxyapatite Coating on Carbon Fiber Cloth |
Author(s) |
Sylvie Bonnamy, Florian Olivier, Sandrine Delpeux, Jérôme Chancolon, Vincent Sarou-Kanian, Franck Fayon, Nathalie Rochet |
On-Site Speaker (Planned) |
Sylvie Bonnamy |
Abstract Scope |
Due to their multi-scale organization, breathability and biocompatibility, carbon fiber cloths are considered as tissue engineering. Owing to high bioactivity, osteoconductivity and biocompatibility, calcium phosphate (CaP) are clinically employed in orthopaedics. In this context, CaP and Sr-CaP coatings deposited on carbon cloths are produced by sono-electrodeposition process to be used as bone regenration. FTIR, XRD, HRTEM and SEM show that CaP coatings consist of plate-like and/or needle-like carbonated calcium-deficient hydroxyapatite depending on electrochemical parameters. 1H and 31P MAS NMR show that CaP particles are composed of an ordered and carbonated CDA core associated with a disordered and hydrated surface layer. Biological tests through in vitro osteoblast culture highlight the cell viability. For in vivo biological tests, bone defect is performed on femur of rats. The application of a hybrid material shows an acceleration of bone regeneration. The introduction of drugs to biomaterial components brings new functionalities to the composite biomaterial. |
Proceedings Inclusion? |
Planned: Supplemental Proceedings volume |