About this Abstract |
Meeting |
2025 TMS Annual Meeting & Exhibition
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Symposium
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Phase Stability, Phase Transformations, and Reactive Phase Formation in Electronic Materials XXIV
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Presentation Title |
Elastin-like recombinamer-mediated hierarchical mineralization coatings on Zr-16Nb-xTi (x = 4,16 wt%) alloy surfaces improve biocompatibility |
Author(s) |
Ligang Zhang, Renhao Xue, Libin Liu |
On-Site Speaker (Planned) |
Ligang Zhang |
Abstract Scope |
We employed a mineralizing elastin-like recombinamer (ELR) self-assembling platform to ediate mineralization on Zr-16Nb-xTi (x = 4,16 wt%) alloy surfaces, resulting in the modification of surface morphology and bioactivity while improving the biocompatibility of the material.Nanoindentation tests revealed that the mineralized configuration had nonuniformity with respect to Young’s modulus and hardness, with the center areas having higher values (5.626 ±0.109 GPa and 0.264 ± 0.022 GPa) compared to the edges (4.282 ± 0.327 GPa and 0.143 ± 0.023 GPa). The
Scratch test results indicated high bonding strength (2.668 ± 0.117 N) between the mineralized coating and the substrate. Mineralized Zr-16Nb-xTi (x = 4,16 wt%) alloys had higher viability compared to untreated alloys,
which exhibited high cell viability (>100 %) after 5 days and high alkaline phosphatase activity after 7 days. Furthermore, hemocompatibility test results revealed that all mineralized samples were non-hemolytic. |
Proceedings Inclusion? |
Planned: |
Keywords |
Biomaterials, Phase Transformations, Surface Modification and Coatings |