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Meeting MS&T22: Materials Science & Technology
Symposium 3D Printing of Biomaterials and Devices
Presentation Title Effect of Sr2+ and Ca2+ ions on 3D printed Beta Tricalcium-Phosphate/Alginate Composite Scaffolds for Bone Tissue Engineering
Author(s) Shebin Tharakan, Sally Lee, Serin Ahn, Chris Mathew, Michael Hadjiargyrou, Azhar Ilyas
On-Site Speaker (Planned) Shebin Tharakan
Abstract Scope Beta-Tricalcium Phosphate (β-TCP) is a bioceramic that is a Calcium Phosphate of Hydroxyapatite, a material commonly used for bone growth. While bioceramics are difficult to 3D print, when placed into composite materials they become printable. Here, we 3D printed β-TCP/Alginate composite scaffolds to evaluate the effect of Sr2+ and Ca2+ ions on their biomechanical properties (swelling, degradation, and Raman profiling). Results show that the presence of Sr2+ slowed down the degradation rate in physiological conditions, with Sr-doped scaffolds having a longer life-span and greater structural fidelity than the respective Ca-doped scaffolds. The Sr-doped scaffolds had greater overall swelling compared to the Ca-doped counterparts. The presence of β-TCP caused a decrease in swelling for Ca-doped scaffolds, likely due to the amount of volume it displaced per scaffold. Furthermore, the scaffold expansion data showed that the scaffolds enlarged up to 24 hours but saturated in size dimensions up to 7 days.


3-D Printing in Regenerative Engineering
3D Bioprinting with Engineered Living Materials for Advanced Biofabrication
3D Printing Integrated with Controlled Delivery for In Situ Tissue Engineering of Complex and Inhomogeneous Tissues from Endogenous Stem/Progenitor Cells
3D Printing of Nanomaterials-based Biomedical Electronics
3D Printing of Zonal-structured Scaffolds for Complex Tissue Engineering
3D Printing Strategies to Fabricate Complex Scaffolds for Tissue Engineering Applications
Additive Manufacturing Process Simulation of Polyetherimide Porous Scaffolds for Bone Tissue Engineering Applications
Biohybrid Functional Material Design by Engineered Peptides
C-1: Surface Treatment of Titanium by Alkali treatment and Magnesium Deposition for Orthopedic Application
Effect of Printing Parameters on 3D-printed Biodegradable Biopolymer-metal Composite Material
Effect of Sr2+ and Ca2+ ions on 3D printed Beta Tricalcium-Phosphate/Alginate Composite Scaffolds for Bone Tissue Engineering
Implant Optimization Guided by Biomimetic Insight
Interlocked Bone Scaffolds with BMP Induced Osteogenesis with Use of 3D Printed Molds
Laser-Based 3D Printing for Medical Applications
Mechanical and Electrical Properties of 3D Printed Wearable Structures
Periodic Cellular Ceramic Structures by Replication of Additive Manufactured Templates
Selective Artificial Neural Network by Targeted Delivery of Neuronal Cells Using Magnetically Controlled 3D Printed Microrobots
Sheet Lamination Additive Manufacturing (SLAM) – A Viable Approach to Resorbable 3D Constructs for Bone Tissue Engineering
Solvent Cast 3D Printing with Different Molecular Weight Polymers
The Regulatory Roles of the Substrate Microenvironment in Cancer Progression in Tissue Engineering Scaffolds

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