Abstract Scope |
Commercial bioactive glasses (BAGs) e.g., S53P4 or 45S5, are limited to granules and putties, pertaining to their high crystallization tendency. To overcome these problems, borosilicate glasses were developed. High boron content was found efficient in producing glasses with fast conversion into hydroxyapatite and with thermal properties allowing processing of porous scaffolds. Therefore, the processing and in-vitro dissolution of newly developed boron-containing BAG will be discussed along with the impact of ion dissolution on cell activity. However, to make a difference in the clinical field, newly developed biomaterials should have added functionalities. In recent years, we have focused in bringing light into darkness. Our research aims at combining luminescent particles into BAG scaffolds, in order to use low light intensity, to direct cell fate. The impact of light (wavelength, intensity) on cell behaviour, and the potential applications, will therefore be presented. |