| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Next Generation Biomaterials
|
| Presentation Title |
C-5: Synthesis and Characterization of Naturally Derived SiO2 and CaO for 45S5 BioactiveGlass for Wound Healing Applications |
| Author(s) |
Samadhan Gaikwad, Vijay H Ingole |
| On-Site Speaker (Planned) |
Samadhan Gaikwad |
| Abstract Scope |
The management of skin damage is assumed an unmet clinical need, and no entirely satisfactory solution to this problem exists to date. Using the sol-gel method, we prepare copper (Cu) doped 45S5 BG from naturally derived biomaterials using beach sand as a source of high purity silica and eggshell biowaste as a source of calcium. Using BET, the results of SiO2 and CaO were highly porous, ranging between 189 and 190 nm. The scaffolds are biomimetic mineralized using simulated body fluid that mimics the inorganic composition of human blood plasma, and hydroxyapatite nucleation is confirmed on the scaffold. The highly vascularized chorioallantoic membrane (CAM) that surrounds the embryo can be used to visually inspect the angiogenic effect of therapeutics applied to the ex-ovo chicken embryo. These findings suggested that bioactive glass derived from natural sources could improve biological properties in wound healing applications. |