| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Next Generation Biomaterials
|
| Presentation Title |
Coating of Hydroxyapatite/Collagen Bone-like Nanocomposite by a Modified Electrophoretic Deposition Method and Its Biological Reaction |
| Author(s) |
Masanori Kikuchi, Tersuo Uchikoshi, Kaori Iwanami-Kadowaki, Hanae Arai, Takeshi Ogasawara, Masayoshi Uezono, Keiji Moriyama |
| On-Site Speaker (Planned) |
Masanori Kikuchi |
| Abstract Scope |
Titanium dip-coated with hydroxyapatite/collagen bone-like nanocomposite (HAp/Col) accelerate osseointegration by thrice faster than that to bare Ti and osteoconduction to nano-HAp coated Ti. As lectured in MS&T2020, We successfully prepared high-adhesive strength coating of HAp/Col on Ti by electrophoretic deposition with use of Mg ions. On the other hand, acceleration of osseointegration depends on coating thickness and/or coating amount of HAp/Col. To determine an optimal coating thickness of HAp/Col EPD coating on Ti for quick osseointegration, HAp/Col EPD coated Ti bars at various coating thickness were implanted into sub-periosteum site of rat’s cranium for 4 weeks. The results indicated that HAp/Col EPD-coated Ti at 20-µm thick successfully accelerate osseointegration as the same as the HAp/Col dip-coated Ti. The animal experiments were conducted under the approval number A2020-121C4 of the Animal Ethics Committee of Tokyo Medical & Dental University. |