| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Next Generation Biomaterials
|
| Presentation Title |
Copper Containing Glass-Based Bone Adhesives for Orthopaedic Applications: Glass Characterization, Antimicrobial Efficacy and Mechanical Suitability |
| Author(s) |
Sahar Mokhtari, Anthony W. Wren |
| On-Site Speaker (Planned) |
Anthony W. Wren |
| Abstract Scope |
Copper (Cu) based glasses have been synthesized for the formation of flexible inorganic-organic polyacrylic acid (PAA) – hybrids, commercially known as glass ionomer cements (GICs). Initial glass characterization includes X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and Raman Spectroscopy to yield structural information on the effect of Cu doping within a SiO2-ZnO-CaO-SrO-P2O5 glass. Antibacterial efficacy was conducted over a range of bacteria (E. coli, S. epidermidis, S. aureus) by employing the agar diffusion and broth dilution method. Cu containing GICs significantly reduced bacterial viability compared to the Cu-free control GICs in under each condition tested. Mechanical evaluation was assessed through compressive strength (CS), biaxial flexural strength testing (BFS) and shear bond strength testing with respect to incubation time in a hydrated medium. Additionally, studies into strain recovery of the Cu-GICs post CS testing will be presented as these materials experience excellent physical recovery when placed in a hydrated environment. |