| About this Abstract |
| Meeting |
2021 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
A Novel Cardiac Patch for Treating Myocardial Infarction |
| Author(s) |
Juan Sebastian Rincon Tabares, Juan Camilo Velasquez, Hayden Bilbo, Hai-Chao Han, David Restrepo |
| On-Site Speaker (Planned) |
Juan Sebastian Rincon Tabares |
| Abstract Scope |
Myocardial infarction (MI) is the most common heart disease. MI leads to scar and aneurysm in the heart wall that deteriorating the pump function and leads to heart failure. Currently,cardiac patches (CPs) are used to strengthen the aneurismal scar tissue to improve cardiac function. Current CPs have two major limitations: (i) CPs can only provide passive support to the scar tissue and no ability to assist heart contraction,(ii) The human heart is highly anisotropic. Our objective was to develop a smart material that could generate shrinkage under tension. Then, it can assist heart contraction and conform better to the native heart movements and mechanical properties. An analytical approach with computational verification was proposed to explore a potential design of architectural material that shrinks under tensile forces. Finally,using physical geometries, the architectural material models have been validated by digital image correlation (DIC). The material shows negative strain values of over 30%. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Modeling and Simulation, Mechanical Properties |