|About this Abstract
||2022 TMS Annual Meeting & Exhibition
||Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
||Acemannan Loaded Mg-doped 3D Printed Multifunctional Scaffolds: In Vivo and In Vitro Biological Property Evaluation
||Ujjayan Majumdar, Susmita Bose
|On-Site Speaker (Planned)
Calcium phosphate-based materials are a suitable choice for bone tissue engineering applications due to its compositional resemblance with natural bone. The flexible crystal structure of these materials allow doping with different transition metals, which enhances their biological and mechanical properties. In recent years, Acemannan, the active compound of aloe vera gel extract has drawn attention to the scientific community due its effects on new bone formation.. The current study aims to investigate the effects of naturally extracted Acemannan on the osteogenic, chemo-preventive and anti-bacterial properties of Mg doped 3D printed Calcium phosphate (CaP) scaffolds. This study will discuss the extraction method of Acemannan from organic aloe vera leaf, the release kinetics of Acemannan from Mg-doped 3D printed CaP scaffolds, and their in-vivo bone formation ability in rat distal femur models as a function of composition and release kinetics.
||Additive Manufacturing, Ceramics, Biomaterials