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Meeting 2022 TMS Annual Meeting & Exhibition
Symposium Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
Presentation Title Curcumin and Vitamin D3 enhances osteogenic and chemopreventive properties of 3D printed CaP bone scaffolds
Author(s) Yongdeok Jo, Susmita Bose
On-Site Speaker (Planned) Yongdeok Jo
Abstract Scope Bone trauma, severe infection, and tumor ablations are causes of critical-sized bone defects which fail to heal on their own. This has reinforced the need for novel multifunctional bone graft to support bone regeneration. Additive manufacturing (AM) has shown advanced bone grafts attaining high accuracy and part complexity in bone defect repair applications. Multifunctional three-dimensional (3D) printing of calcium phosphate scaffolds with natural biomolecules presents a new trend in patient-matched implants to facilitate bone healing and chemoprevention. Curcumin has attracted much interest due to its wide range of therapeutic uses for chemoprevention and osteoporosis. Vitamin D3, which is needed to absorb calcium in the body, is an essential nutrient to maintain bone health. We have fabricated the 3D printed scaffolds with designed porosity, matching trabecular bone strength. Dual drug delivery of curcumin and vitamin D3 from the scaffolds induced apoptosis in osteosarcoma cells and enhanced in vitro osteoblast cell proliferation.
Proceedings Inclusion? Planned:
Keywords Biomaterials, Ceramics, Additive Manufacturing

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

4D Printable Salicylic Acid Photopolymers for Sustained Drug-Releasing, Shape Memory Soft Tissue Scaffolds
Acemannan loaded Mg-doped 3D printed multifunctional scaffolds: In vivo and in vitro biological Property evaluation
Additive manufacturing of natural materials as a multidisciplinary approach in Engineering Education
Biofilm Formation on Titanium Fabricated using Additive Manufacturing
Combining Traditional Electronics Packaging and NanoJet Aerosol Printing to Develop an Implantable High-density In-line Connector
Curcumin and Vitamin D3 enhances osteogenic and chemopreventive properties of 3D printed CaP bone scaffolds
Development and 3D Printing of a Bioabsorbable Composite Material for Orthopaedic Applications
Effect of Unit Cell Topology on the Mechanical Properties of Co-Cr-Mo Triply Periodic Minimal Surface Lattices Fabricated by Selective Laser Melting
Effects of Cell Sedimentation on Droplet Formation Process and Cell Distribution during Inkjet Printing of Cell-Laden Bioink
Effects of Topographic Parameters on a Micropillar Surface on Cell Migration and Morphology
Femto-second laser lithography of fluorescent 2D/3D nanostructures
Gingerol – Curcumin loaded Magnesium – Zinc Doped Calcium Phosphate Based Scaffolds and Coatings for Bone Tissue Engineering Applications
Influence of strut-size and cell-size variations on additively manufactured porous Ti6Al4V
Multifunctional Artificial Artery from Direct 3D Printing with Built-in Ferroelectricity and Tissue-Matching Modulus for Real-Time Sensing and Occlusion Monitoring
Prediction of Cell Viability in Dynamic Optical Projection Stereolithography-Based Bioprinting Using Machine Learning
Synthesis and Characterization of Hydroxyapatite from Solid Mineral for Dental and Orthopedic Applications

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