| About this Abstract |
| Meeting |
2022 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
|
| Presentation Title |
Multifunctional Artificial Artery from Direct 3D Printing with Built-in Ferroelectricity and Tissue-matching Modulus for Real-time Sensing and Occlusion Monitoring |
| Author(s) |
Jun Li |
| On-Site Speaker (Planned) |
Jun Li |
| Abstract Scope |
In this work, electric field-assisted 3D printing technology was developed to fabricate in situ-poled ferroelectric artificial arteries. The complex functional artery architecture was made by the development of a printable ferroelectric bio-composite which could be quickly polarized during printing and reshaped into devised objects. Synergistic effect from the ferroelectric potassium sodium niobate (KNN) particles and the ferroelectric polyvinylidene fluoride (PVDF) polymer matrix yielded a superb piezoelectric performance (bulk-scale d33 > 12 pC N-1). The sinusoidal architecture brought the mechanical modulus down to the same level of human blood vessels. The desired piezoelectric and mechanical properties of the 3D-printed artificial artery provided an excellent sensitivity to pressure change (0.306 mV/mmHg, R2> 0.99) within the range of human blood pressure (11.25 to 225.00 mmHg). The high pressure sensitivity and the ability to detect subtle vessel motion pattern change enabled early detection of partial occlusion (e.g., thrombosis), allowing for preventing grafts failure. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, Biomaterials, Energy Conversion and Storage |