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Meeting 2022 TMS Annual Meeting & Exhibition
Symposium Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
Presentation Title Gingerol – Curcumin loaded Magnesium – Zinc Doped Calcium Phosphate Based Scaffolds and Coatings for Bone Tissue Engineering Applications
Author(s) Arjak Bhattacharjee, Susmita Bose
On-Site Speaker (Planned) Arjak Bhattacharjee
Abstract Scope Transition metal-doped hydroxyapatite (HA), and tricalcium phosphate (TCP) based materials are suitable candidates for bone tissue engineering applications due to their tailored biological properties, and compositional similarities with human hard tissues. Gingerol, the active compound of ginger root and curcumin from turmeric are two important natural medicinal compounds with chemo-preventive potential. In the current work, gingerol and curcumin are incorporated on Mg - Zn doped HA, and TCP to assess the biological properties. Osteoblast cell viability increases up to ~ 1.3 folds on day 11 of cell culture, which can be attributed to the osteogenic potential of each component. The presence of Zn and curcumin show ~ 75% more antibacterial efficacy compared to control after 36 hrs of sample – bacteria interaction. This presentation will discuss the fabrication of the gingerol – curcumin-loaded scaffolds and their anti-bacterial, osteogenic, and chemo-preventive potential for possible applications in patient-specific defect repair sites.
Proceedings Inclusion? Planned:
Keywords Additive Manufacturing, Surface Modification and Coatings, Biomaterials


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Effects of Topographic Parameters on a Micropillar Surface on Cell Migration and Morphology
Femto-second laser lithography of fluorescent 2D/3D nanostructures
Gingerol – Curcumin loaded Magnesium – Zinc Doped Calcium Phosphate Based Scaffolds and Coatings for Bone Tissue Engineering Applications
Influence of strut-size and cell-size variations on additively manufactured porous Ti6Al4V
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