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Meeting 2022 TMS Annual Meeting & Exhibition
Symposium Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
Presentation Title Biofilm Formation on Titanium Fabricated using Additive Manufacturing
Author(s) Mari Koike, Susan K Hummel, Richard J Mitchell, Toru Okabe
On-Site Speaker (Planned) Mari Koike
Abstract Scope This study was to determine the biofilm accumulation of titanium alloys fabricated with additive manufacturing that have possessed desirable characteristics for biomedical applications. Disks (10 mm dia. x 2 mm thick) of Ti-6Al-4V alloy were fabricated with the following techniques: electron beam melting (EBM) by additive manufacturing (AM), laser beam melting (LBM), or lost-wax technique using a centrifugal casting machine. Teflon was used as controls. After sterilizing specimens, each specimen (n=6/condition) was placed in each well and incubated statically with Candida albicans (CA, ATCC MYA2876). After 48-hour, the viability of CA adhering to each specimen was determined using a bioluminescence assay. Ti-6Al-4V specimens made by AM showed less biofilm accumulation than the as-cast specimens. The surface of Ti specimens by EBM-AM are bumpier but smoother than the as-cast specimens. In this test period, it appears that surface roughness as measured by Sa does not correlate to biofilm accumulation.
Proceedings Inclusion? Planned:
Keywords Additive Manufacturing, Biomaterials, Titanium


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