|About this Abstract
||2022 TMS Annual Meeting & Exhibition
||Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
||Biofilm Formation on Titanium Fabricated using Additive Manufacturing
||Mari Koike, Susan K Hummel, Richard J Mitchell, Toru Okabe
|On-Site Speaker (Planned)
This study was to determine the biofilm accumulation of titanium alloys fabricated with additive manufacturing that have possessed desirable characteristics for biomedical applications. Disks (10 mm dia. x 2 mm thick) of Ti-6Al-4V alloy were fabricated with the following techniques: electron beam melting (EBM) by additive manufacturing (AM), laser beam melting (LBM), or lost-wax technique using a centrifugal casting machine. Teflon® was used as controls. After sterilizing specimens, each specimen (n=6/condition) was placed in each well and incubated statically with Candida albicans (CA, ATCC MYA2876). After 48-hour, the viability of CA adhering to each specimen was determined using a bioluminescence assay.
Ti-6Al-4V specimens made by AM showed less biofilm accumulation than the as-cast specimens. The surface of Ti specimens by EBM-AM are bumpier but smoother than the as-cast specimens. In this test period, it appears that surface roughness as measured by Sa does not correlate to biofilm accumulation.
||Additive Manufacturing, Biomaterials, Titanium