|About this Abstract
||2022 TMS Annual Meeting & Exhibition
||Functional Nanomaterials: Functional Low-Dimensional (0D, 1D, 2D) Materials 2022
||LED Assisted Synthesis and Excitation of Silver Nanoparticles for Plasmon-enhanced Antibacterial Effects
||Connor Bourgonje, Juan C. Scaiano
|On-Site Speaker (Planned)
In this work, we expand on a seed-mediated silver nanoparticle (AgNP) synthesis which utilizes LED illumination to control the morphology and optical properties of citrate capped AgNPs. This method eliminates the need for surfactants (such as CTAB) to control AgNP shape, allowing for wavelength-dependent growth of decahedral, spherical, or triangular AgNPs with tunable sizes and absorbance bands spanning the entire visible and NIR spectrum. Using this method, we were able to synthesize triangular AgNPs with strong plasmonic absorbance in the biological window, the region in the visible/NIR region where photons can best penetrate biological samples. Under illumination with NIR LEDs the antibacterial activity of these AgNPs increases by several orders of magnitude, requiring only minutes to achieve 8 Log reductions in bacterial CFU counts. These preliminary results show great promise in enhancing the effectiveness of AgNPs, showcasing their immense potential as antibacterial and phototherapeutic agents when paired with LED illumination.
||Biomaterials, Nanotechnology, Characterization