Noble metal nanoparticles exhibit localized surface plasmon resonance (LSPR) when interacting with light, which has been studied for applications such as catalysis, biosensing, gas detection, and chemical sensing. One commonly used material in hydrogen sensing is palladium, which can dissociate hydrogen gas and form a hydride, resulting in a shift of the LSPR absorption. Core-shell nanoparticles consisting of a noble metal core and a shell material, such as a transition metal oxide, could provide a material system for hydrogen detection with a more permanent plasmonic shift during exposure to hydrogen. In this work, we show the synthesis of various noble metal core-shell nanoparticles, including gold-copper (I) oxide and gold-palladium, with spherical and spiked structures and evaluate their ability to detect hydrogen in colloidal suspensions. In addition, we will discuss electrochemical methods to synthesize core-shell nanoparticles and spectroelectrochemistry to characterize the nanoparticles during growth.