| Abstract Scope |
The use of matrix assisted pulsed laser evaporation for processing thin films offers several advantages over dip coating, spin coating, and Langmuir-Blodgett dip coating. The matrix assisted pulsed laser evaporation approach can be used to precisely control the thickness of thin films. The matrix-assisted pulsed laser evaporation method also allows for excellent control of film roughness. Additionally, matrix assisted pulsed laser evaporation is a "cold" process that does not heat biological molecules. In recent studies, matrix assisted pulsed laser evaporation has been used to prepare several types of films containing antimicrobial and antiproliferative drugs. In this presentation, in vitro studies involving matrix assisted pulsed laser evaporation-processed thin films involving bacterial, fungal, and mammalian cells will be presented. The results of these studies indicate that the thin films containing antimicrobial and antiproliferative drug grown by matrix assisted pulsed laser evaporation exhibit appropriate functionality for many medical device applications. |