2D materials are emerging materials for bioelectronics. We have invented a cost- and time-effective “cut-and-paste” process for the rapid prototyping of CVD graphene e-tattoos (GETs). Tensile fracture of PMMA-supported graphene has been experimentally investigated and different stages of fracture have been identified. GET can fully conform to the microscopic morphology of the skin surface via just van der Waals forces. As a dry electrode, GET-skin interface impedance is found to be as low as medically used Ag/AgCl gel electrodes. GET has been successfully applied to measure electrocardiogram (ECG), electromyogram (EMG), electroencephalogram (EEG), electrooculogram (EOG), skin temperature, and skin hydration. Noninvasive functionalized graphene glucose sensor can be integrated with transdermal drug-delivery microneedles. Wireless e-tattoos exploring the modular and reconfigurable design will be introduced. In addition to noninvasive e-tattoos, we have engineered human eye-inspired implantable curved image array using atomically thin MoS2-graphene heterostructure.