|About this Abstract
||MS&T22: Materials Science & Technology
||3D Printing of Biomaterials and Devices
||C-1: Surface Treatment of Titanium by Alkali treatment and Magnesium Deposition for Orthopedic Application
||Sahar Vahabzadeh, Dexter Kling, Paige Bothwell
|On-Site Speaker (Planned)
Titanium (Ti) and titanium alloys are the most common metals for hard tissue engineering applications. However, implant loosening results in failure which demands revision surgeries. Surface modification of 3D printed Ti by chemical and physical methods are common to improve anchoring of bone tissue with titanium implants. In current work, alkali-treatment and immersion methods were used to roughen the titanium surface and deposit magnesium (Mg) on surface of titanium at different concentrations. Mg is a key element in bone development and its deficiency is linked to low bone mass density. Our results show that alkali-treatment using 10 M NaOH solution results in a uniform network structure. Mg was successfully deposited by immersion of alkali-treated Ti in magnesium nitrate solution, deposition amount increases gradually with increase in concentration of Mg precursor up to 0.234 M, and osteoblast cell proliferation was significantly affected by presence of Mg, as determined by MTT assay.