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Meeting Materials Science & Technology 2020
Symposium Next Generation Biomaterials
Presentation Title Ultra-soft Hydrogel Mechanical Property Testing Device and Methodology
Author(s) Kazue Orikasa, Nicole Bacca, Arvind Agarwal
On-Site Speaker (Planned) Kazue Orikasa
Abstract Scope Recently, new ultra-soft materials such as hydrogels have led to advances in biomaterial development. Hydrogels are used as a scaffold material for tissue regeneration. It is essential to understand the mechanical properties of scaffolds as there is a correlation between their mechanical properties and the conditions for cell growth. Although there are methods available for measuring the mechanical properties of ultra-soft materials, they often require high specialization and sophisticated equipment. A simple device and methodology for ultra-soft material characterization are proposed. A 10 mm-diameter cylindrical flat indenter constructed from a stiff polymer was designed and attached to a table-top mechanical load frame. Indentation tests on natural soft materials with varying stiffness (e.g. high-fat yogurt, chicken breast, Aloe Vera) were conducted. A variation of the Johnson-Kendall-Roberts technique was applied to compute the stiffness values. The results suggest that novel device and methodology provide accurate values of compliant materials.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

3D Printed Porous Tissue Engineering Scaffolds with the Self-folding Ability and Controlled Release of Growth Factor
3D Printed Strontium-doped Alginate-collagen Scaffolds for Bone Tissue Engineering
4D Printing of Advanced Scaffolds with Controlled Growth Factor Delivery for Tissue Engineering
A Failing Healthcare System with Decreasing Life Expectancies: Are Conventional Biomaterials to Blame?
Bioceramics in the Ca2P2O7 – Mg2P2O7 System with a Tailored Architecture for Bioimplantation
Biocompatible Ceramics Based on Hydrated Calcium Phosphates
Biomimetic Patterns of Metallic Nanoparticles for Antimicrobial Applications
Chemical, Thermal and Radiological Stability of Bio-ceramics
Corrosion Modelling of Coated Pure Magnesium Towards Degradation-Controlled Bone Fixation Implants
Creating Smart Biopolymer Fibers for Healthcare Applications
Decellularized Lucky Bamboo (Dracaena sanderiana) Scaffolds for Bone Tissue Engineering
Diamond-like Carbon Thin Films for an Improved Surgical Field of View
Fibrin-modulating Nanogels for the Treatment of Disseminated Intravascular Coagulation
Functionalization of Titanium for Biomedical Use
Mechanical Behavior of Resilin-mimicking Materials
Nanostructured Surface Bioactive Composite Scaffold for Filling of Mandibular Bone Defects: A Pilot Study
New Materials for Medical Implants: Diamond
Next Generation Multi-principal and Amorphous Metallic Biomaterials
Novel Hierarchical Carbon Nantotube-coated Materials as Bioscaffolds for Keratinocyte Cell Growth
Optimizing Bicontinuous Structure of Bijels-derived Polymer-hydrogel Hybrids for the Controlled Release of Different Cells
Photopolymerization-Based 3D Printing of Medical Devices
Powder Mixtures of Calcium Hydroxyapatite and Potassium Hydrosulfate for Producing Biocompatble Ceramics
Silk Fibroin Scaffold Degradation Induced by Focused Therapeutic Ultrasound
Stereolithographic Additive Manufacturing of Bioceramic Implants
Three High Entropy Alloys and their Ability to Control Biofilm Formation
Ultra-soft Hydrogel Mechanical Property Testing Device and Methodology

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