| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
|
| Presentation Title |
Effects of Post-printing Cell Distribution on Cell Viability and Proliferation in Inkjet-based Bioprinting of Vascular Structures |
| Author(s) |
Jiachen Liu, Changxue Xu |
| On-Site Speaker (Planned) |
Changxue Xu |
| Abstract Scope |
Inkjet-based bioprinting has been widely used to fabricate 3D structures based on a layer-by-layer manner for various applications in tissue engineering and regenerative medicine. The bioink used is considered as a suspension incorporating living cells. Because the typical bioprinting process may take several hours, the suspended cells in the bioink sediment and aggregate at the bottom of the bioink reservoir, which results in non-uniform post-printing cell distribution within the fabricated structures. The non-uniform cell distribution significantly affects the eventual functionality of the fabricated structures. This paper focuses on the comparison of uniform and non-uniform post-printing cell distribution effects on post-printing cell viability and proliferation. It shows that compared to non-uniform cell distribution the uniform cell distribution significantly improves cell viability (92% vs 77% at Day 3) and cell proliferation (3.3 times vs 1.7 times at Day 3). |
| Proceedings Inclusion? |
Planned: |