| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
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| Presentation Title |
Graphene and MXene Nanomaterial Bioinks for Improvement of 3D Bioprinted Tissue Engineering |
| Author(s) |
Miranda L. Nelson, Hailey M. Burgoyne, Annaka Tibbits, Fereshteh Rajabi-Kouchi, Tony Valayil Varghese, Raquel Montenegro-Brown, Josh Eixenberger, David Estrada |
| On-Site Speaker (Planned) |
Miranda L. Nelson |
| Abstract Scope |
Bioprinting has created the opportunity for expanding the use of nanomaterials in 3D hydrogel scaffolds. The inclusion of 2-dimensional nanomaterials such as graphene and Ti3C2 MXenes, into bioinks has been shown to increase printability and influence the physical properties of printed bioscaffolds to better reflect physiological environments. Here we show a comprehensive characterization of the inclusion of MXene and graphene nanoflakes into printed alginate cellulose based bioscaffolds. The resultant scaffolds were characterized by atomic force microscopy as well as scanning electron microscopy. The Van der Pauw method was used to ascertain the conductivity of each scaffold type. C2C12 cells were then seeded in the bioprints and a viability assay and gene expression were performed. Understanding the effects of the inclusion of these nanomaterials will create opportunities for scaffolds that can be more precisely tuned for each tissue type and may allow for electro-stimulus to be used on hydrogel bioprinted scaffolds. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, |