| About this Abstract |
| Meeting |
2024 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
|
| Presentation Title |
Bioabsorbable PLDL/Mg-wire Composites Manufactured by Fused Filament Fabrication for Tissue Engineering |
| Author(s) |
Cillian Thompson, Carlos González, Javier Llorca |
| On-Site Speaker (Planned) |
Javier Llorca |
| Abstract Scope |
Bioabsorbable polymers based on poly-lactic acid (PLA) are currently used to manufacture scaffolds for tissue repair that gradually disappear and neither hinder the growth of natural tissue nor require a second surgery for removal. However, their mechanical properties are limited for non-load-bearing applications and the degradation time is often too long (up to years). These limitations can be overcome by reinforcing PLA with Mg wires that improve the stiffness and strength and accelerate the degradation.
PLA/Mg-wire composites were manufactured by fused filament deposition and their mechanical, degradation and biological performance was assessed by means of in vitro tests at 37ºC. These novel materials open the way to the fabrication of multimaterial scaffolds by 3D printing in which different bioabsorbable materials (PLA, PLA reinforced with Mg or Zn particles and PLA reinforced with Mg wires) can be used to tailor the properties of material in each region of the scaffold. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Magnesium, Composites |