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Meeting MS&T23: Materials Science & Technology
Symposium Society for Biomaterials: Student Poster Contest + Rapid Fire
Presentation Title C-16: Carvacrol and Curcumin: Potential Therapeutic Agents for Bone Defects Treatment
Author(s) Aditi Dahiya, Susmita Bose
On-Site Speaker (Planned) Aditi Dahiya
Abstract Scope Phytochemicals have received wide attention due to their therapeutic potential in treating various diseases. Carvacrol and curcumin are compounds that show promising results in bone tissue engineering. This study investigates the cell-material interactions of carvacrol on calcium phosphate matrices. The findings demonstrate that carvacrol inhibits osteoclast cell viability and enhances the differentiation of human mesenchymal stem cells into osteoblasts. The bioactivity of carvacrol, when encapsulated in nanoparticles, increases its antibacterial efficacy and osteoblast cell viability while reducing osteosarcoma cell viability. The study also explores the synergistic effects of carvacrol and curcumin through nanoparticle encapsulation. The results indicate that the nanoparticle-treated scaffold promotes osteoblast cell activity and inhibits bacterial and osteosarcoma cell growth. These findings suggest the potential natural medicinal compounds within nano drug delivery vehicles on calcium phosphate scaffolds in developing personalized therapeutic implants for bone-related disorders.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

C-13: Bioelectricity and Biomarker Acid Dual Targeting Fe3O4@Cu2-xS Nanoparticles for Photothermal Cancer Cell Killing
C-15: Blow Spinning of Polyvinyl Alcohol (PVA) and Polyvinylpyrrolidone (PVP) Scaffolds Embedded with Zinc Halloysite Nanotubules (HNTs)
C-16: Carvacrol and Curcumin: Potential Therapeutic Agents for Bone Defects Treatment
C-17: Effect of Patient-specific Blood Biomarkers on Nanoparticle-cell Interactions
C-18: Electrochemical Performance of EF-hand Peptide Conjugated with Tyrosine as an Aptamer for the Biosensing of Rare Earth Elements
C-19: Formulation of Biodegradable Polysaccharide Blend As Replacement of Single Use Plastic
C-20: Identifying Fouling Mechanisms of Polyproline II Helix Peptides on Gold Surface
C-21: Improvement and Validation of Computational Model of Biliary Stent Behavior
C-22: Investigation of Strontium-Copper-Dopped Sol-gel Bioglass for Soft-tissue Repair
C-23: Loading and Elution Efficiency of T2DA Loaded on Electrospun Chitosan Decanoic and Hexanoic Modified Membranes via Soaking Method
C-25: Mixed Brownian Alignment and Néel Rotations in Superparamagnetic Iron Oxide Nanoparticle Suspensions Driven by an AC Field
C-26: Nanoparticle-based drug delivery for the degradation of recalcitrant blood clots
C-27: Natural Medicinal Compounds Enhance Osteogenic and Antibacterial Properties of Calcium Phosphate-coatedTitanium
C-28: Raman and SEM-EDAX Analysis of Lithium and Gallium Doped Silicate and Borosilicate Sol Gel Bio Glasses for Anti Inflammatory Response
C-29: Synthesis and Characterization of Mesoporous β-Tricalcium Phosphate Powders Using Spray Drying for Orthopedic Applications
C-31: Evaluation of Hemostatic Properties of Procoagulant Synthetic Platelets
C-32: Detection of TIC-relevant Phenotypes with a Multichannel Miniaturized Dielectric Coagulometer Incorporating Bioactive Reagent-functionalized Electrodes

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