About this Abstract |
Meeting |
MS&T21: Materials Science & Technology
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Symposium
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Preceramic Polymers; Synthesis, Processing, Modeling, and Derived Ceramics
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Presentation Title |
Synthesis and 3D Printing of Antibacterial Polymer-derived Bioceramic Scaffolds for Bone Engineering Applications |
Author(s) |
Joelle El Hayek, Laurence Soussan, Philippe Miele, Mikhael Bechelany, Chrystelle Salameh |
On-Site Speaker (Planned) |
Chrystelle Salameh |
Abstract Scope |
Bioceramics, widely used for bone engineering due to their biocompatibility and tunable properties, generally display poor antibacterial activity. Infection at the site of implantation can cause failure in bone healing process; therefore, developing antibacterial bioceramics with good mechanical and microstructural properties is required. In this work, customized 3D β-Ca2SiO4 structures were fabricated by combining the PDCs route and Stereolithography-3D printing. β-Ca2SiO4 scaffolds have been successfully manufactured starting from commercial silicone polymer and inorganic oxide fillers mixed with a biobased photosensitive resin and a “home-made” photosensitive preceramic polymer. After pyrolysis, the scaffolds were functionalized by silver nanoparticles uniformly dispersed on graphene oxide. XPS and TEM analysis along with EELS confirmed the formation of silver nanoparticles throughout the graphene oxide with average particle diameter of 30nm. The antibacterial activity was demonstrated on Escherichia coli. Due to their interconnected porosity, mechanical and antibacterial properties, these cytocompatible scaffolds appear suitable for bone engineering. |