| About this Abstract |
| Meeting |
MS&T23: Materials Science & Technology
|
| Symposium
|
Controlled Synthesis, Processing, and Applications of Structural and Functional Nanomaterials
|
| Presentation Title |
Iron Nanoparticles for Magnetic Imaging Applications |
| Author(s) |
Aleia Williams, Lu Liu, Charles E. Johnson, Jacqueline A. Johnson |
| On-Site Speaker (Planned) |
Aleia Williams |
| Abstract Scope |
Iron based nanoparticles have shown promise in biomedical applications by possessing diagnostic and therapeutic capabilities. Currently, superparamagnetic iron oxide nanoparticles (SPIONs) are the standard magnetic materials used for magnetic based imaging and hyperthermia therapeutics due to their good magnetic properties, biocompatibility, and stability. However, further improvement of iron-based nanoparticles for such applications can be achieved by creating nanoparticles that possess a pure iron core. Therefore, this study investigates a facile, one-pot synthesis of superparamagnetic iron core-shell nanoparticles using a thermal decomposition of iron pentacarbonyl. Monodisperse, spherical, 14 nm iron core-shell nanoparticles were created and coated with a DSPE-mPEG polymer. Coated particles displayed good biocompatibility and stability up to 3 months in refrigeration. From the results, metallic iron nanoparticle displayed magnetic saturation up to 133 emu/g and have the potential to provide improved performance in magnetic resonance imaging, magnetic particle imaging, and magnetic hyperthermia based applications compared to SPIONs. |