| About this Abstract |
| Meeting |
MS&T23: Materials Science & Technology
|
| Symposium
|
Society for Biomaterials: Biomaterial Applications in Today’s Industry: Development, Translation & Commercialization
|
| Presentation Title |
Nanostructured K-wires, Potential Biomedical Applications for UFG 316L |
| Author(s) |
Bahram Saleh, Manoj Kodigudla, David Dick, Amey Kelkar, Vijay Goel, Girius Antanaitis, Fumie Yusa, Yasuaki Osawa, Ryosuke Mizuno, Takafumi Komatsu, Hassan Serhan |
| On-Site Speaker (Planned) |
Bahram Saleh |
| Abstract Scope |
Kirschner wires (K-wires) are a common fixation device in foot, ankle, wrist, and finger surgery in adults, and immensely versatile in fracture fixation in the pediatric population. Complications associated with the K-wiring include breakage and migration to vital structures in the body as well as pin tract infection. Ultrafine-grained (UFG) (grain size <1,000 nm) stainless steel 316L were used to make a new generation of K-wire. UFG materials have a homogeneous microstructure that resulted in improved fatigue performance, reduced biofilm formation, and reduced post machining process cost. Our K-wires made from UFG 316L are ~20-40% stronger than conventional K-wires and have shown lower in vitro bacterial adhesion using different gram-positive bacteria vs. standard K-wires (i.e., staph aureus and staph epidermidis). Previous studies have shown inhibiting bacterial adhesion is essential to prevent implant associated infection, and we are currently evaluating the anti-infective properties of our K-wires using in vivo animal studies. |