| About this Abstract |
| Meeting |
MS&T21: Materials Science & Technology
|
| Symposium
|
Porous Materials for Biomedical Applications
|
| Presentation Title |
Multifunctional Artificial Artery from Direct 3D Printing with Built-in Ferroelectricity and Tissue-matching Modulus for Real-time Sensing and Occlusion Monitoring |
| Author(s) |
Jun Li |
| On-Site Speaker (Planned) |
Jun Li |
| Abstract Scope |
Treating vascular grafts failure requires complex surgery procedures and associates with a high mortality rate. Real-time monitoring vascular systems could initiate safer treatments in the early stage. In this work, an artificial artery was made by processing ferroelectric bio-composite that could be quickly in-situ poled during printing and reshaped into devised objects with superb piezoelectric performance (d33 > 12 pC N-1, confirmed by piezometer) close to commercial ferroelectric polymers. Its designated sinusoidal architecture brought the mechanical modulus down to the same level of human blood vessels. The desired piezoelectric and mechanical properties of the 3D-printed artificial artery provided an excellent sensitivity to pressure change (0.306 mV/mmHg, R2> 0.99) within the range of human blood pressure. The ability to detect subtle vessel motion change enabled early detection of thrombosis, allowing for preventing grafts failure. This work demonstrated a promising strategy of incorporating multi-functionality into artificial biological systems for smart healthcare systems. |