|About this Abstract
||MS&T21: Materials Science & Technology
||Porous Materials for Biomedical Applications
||P2-7: 3D Printing Seamless Hydrogels for In-vivo Pressure Sensing Devices
||Ashwin Velraj, Jeffrey Scott Bates
|On-Site Speaker (Planned)
Novel additive manufacturing technologies have inspired researchers to explore materials that can deliver desired functionalities within a complicated design structure. The use of custom biomaterials as inks for 3D-printing has been explored to curate features that are otherwise near-impossible to obtain through conventional methods where structural delamination causes device failures. Here, we investigate the customization of Stereolithography (SLA) printing of polymer bio-inks using UV-photo-crosslinking mechanism to obtain a seamless single walled hydrogel tube construct with cross-sectional diameters ranging from 3000 to 100 microns. An aqueous composition of acrylated gelatin and poly(ethylene glycol) with biocompatible photo-initiators sensitive to 405 nm UV radiation are explored as bioinks for SLA 3D-printing. Such material compositions are great candidates in implantable device fabrication that react to bodily changes in a controlled manner. Further development of these hydrogel tubes by embedding pressure sensing circuitry, allows dynamic measurement of pressure changes within the eye to monitor glaucoma.
||Planned: At-meeting proceedings