Microstructural characterization during deformation is vital for the understanding of material response and quantifying aging effects on strength. Traditional post-mortem techniques, while valuable, are limited in their ability to unravel complex mechanistic histories. Advanced real-time, non-destructive techniques like Bragg Coherent Diffraction Imaging (BCDI) can offer insights beyond these limitations, but they are often limited by uncertainties in the phase angle and the inversion process. To address these issues, atomistic simulations have been used to supply bounds on the missing information, where they are relatively inexpensive, statistically robust, and capable of mirroring experimental timescales. However, the lack of complementary characterization tools often limits the direct corroboration of modeling and experimental observations. This presentation explores the development and application of virtual characterization tools for materials subjected to harsh conditions. The focus will be on the observed correlation and the ability to fingerprint diffraction patterns of dynamically deformed materials. Additionally, the presentation will explain the enhancement of data extraction from advanced X-ray sources in near- and mid-field regimes. Lastly, the development of a novel virtual texture analysis tool, "VirTex," will be discussed, demonstrating its ability to decode phase transformation and twinning mechanisms in polycrystalline microstructures.