|About this Abstract
||2022 TMS Annual Meeting & Exhibition
||Advanced Functional and Structural Thin Films and Coatings
||Grafting Phosphonic Acid Polymers onto Titanium Implant by UV Irradiation
||Caroline Pereira, Véronique Migonney, Céline Falentin-Daudré
|On-Site Speaker (Planned)
Titanium (Ti) and its alloys are considerably used as biomaterials for hard tissue replacements. These materials have excellent physical and chemical properties such as good corrosion resistance, acceptable biocompatibility, and mechanical properties close to human bone. However, unmodified Ti-based materials bind to the host tissue poorly. Different techniques have been proposed to enhance bone growth around the implant. One interesting method is grafting bioactive polymers. Previous studies carried out in our laboratory have shown that polymers such as poly (sodium styrene sulfonate) (polyNaSS), poly (methacrylic acid) (polyMA) can favor osteoblast cell adhesion and differentiation. In this context, we propose to chemically modify Ti with a phosphonic acid-based polymer, poly (vinyl benzyl phosphonic acid) (polyVBP). This study assessed poly(VBP) grafting's effect on Ti surfaces and its bioactivity. Ti grafted samples showed significantly better response with osteoblast cells, related to enhanced interaction between cells and the surface due to phosphonate groups' presence.