Rapid solidification leads to formation of various crystalline defects, including vacancy trapping, formation of high dislocation densities, formation of metastable pre-precipitates, and gradients and splitting of crystalline orientation. These crystalline defects critically affect material's mechanical properties, and ultimately contribute to more complex material performance features such as high-cycle fatigue resistance. Therefore it is important to understand the formation mechanisms of the aforementioned defects, and how they depend on the solidification conditions and alloying, in order to better predict and control their formation for designing better and more reliable structural materials. To illuminate the formation mechanisms of these microstructural features, we conduct a multiscale modeling analysis consisting of bond order potential based molecular dynamics (MD), phase field crystal (PFC) method, and sequentially coupled thermomechanical phase field - crystal plasticity scheme. We discuss how the atomistic approaches (MD, PFC) can be used to calibrate continuum level crystal plasticity models.