| About this Abstract |
| Meeting |
2020 TMS Annual Meeting & Exhibition
|
| Symposium
|
Energy Technologies and CO2 Management Symposium
|
| Presentation Title |
Improving In-vitro and In-vivo Antibacterial Functionality of Mg Alloys Through Micro-alloying with Sr and Ga |
| Author(s) |
Xiaobo Chen |
| On-Site Speaker (Planned) |
Xiaobo Chen |
| Abstract Scope |
This study attempts to address such germ-infection issues through controlled release of antibacterial species from bulk gallium (Ga) and strontium (Sr) containing magnesium (Mg) alloys. To validate such a conceptual framework, Mg alloys containing micro-level concentrations of Ga and/or Sr (0.1 wt.%) are employed as model materials, along with commercially pure Mg and titanium (Ti) as control groups. Results demonstrate that such a lean addition of Ga and/or Sr reduces the degradation kinetics of Mg matrix, and the release of Ga3+ ions plays a crucial role in disabling the viability of all selected bacterial strains. The histological tests confirm that the growth of fibrous tissue has been accelerated in the vicinity of Mg-based implants, in comparison to that of blank and c.p. Ti controls. It is also striking that the smallest number density of S. aureus bacteria on the surface of the retrieved Ga-containing Mg rod implants. |
| Proceedings Inclusion? |
Planned: |