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Meeting MS&T22: Materials Science & Technology
Symposium Society for Biomaterials: Biological Response to Materials and Material’s Response to Biological Environments
Presentation Title Architected Biomaterials for Multifunctional Medical Implants
Author(s) Kaveh Barri, Qianyun Zhang, Amir H. Alavi
On-Site Speaker (Planned) Amir H. Alavi
Abstract Scope Multifunctional implants with therapeutic benefits and diagnostic capabilities can revolutionize the healthcare system. One of the majors challenged ahead of developing such smart implants is the lack of biomaterials with novel properties and advanced functionalities. Here, we propose a new generation of architected biomaterials to enable creating multifunctional implantable devices with mechanical tunability, diagnostic and self-powering functionalities. The proposed concept is based on the rational design of material systems with built-in energy harvesting mechanisms. We highlight various aspects of the architected biomaterials by developing proof-of-concept orthopedic implants. We perform bench-top testing using human cadaver spine models to demonstrate the feasibility of using the developed implants for self-powered monitoring of bone healing, without using any external power source. We discuss the capacity of the proposed concept for opening avenues for the next stage of the revolution in smart implantable devices which could be used by clinicians to achieve better surgical outcomes.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Antibacterial Activity of Titanium-based Material Systems
Architected Biomaterials for Multifunctional Medical Implants
Biodegradable Magnesium-based Bone Fixation Implants: Alloy Design, Post-fabrication Processes, and Biocompatibility
Biological Response to Medical Implants: The Good, The Bad, and The Ugly
Biomaterial-induced Activation of the Blood Coagulation Cascade
Bone Formation via Acoustic Radiation Force: Transdermal Stimulation of Hydrogel-encapsulated Stem Cells
C-6: Cell-scaffold Interactions in Bijels-derived Porous Membranes
C-7: Modeling a Portable Ventilator Design for Optimal Performance
C-8: Osteoblast Cell Interaction with Iron-deposited Titanium for Orthopedic Applications
Effects of Debindering Temperature of Carbonate Apatite Honeycomb on Osteoconductivity
Effects of Phospholipid Saturation and Cholesterol Concentration on Liposome Interaction with Fungal and Mammalian Cells
Modeling the Reliability and Proof Testing of Bioceramics
Nanoceria as an Enzyme Mimic ( NEM).
Scalable Green Electrospinning of an Environmentally Safe Nanofibrous Fish Skin Gelatin Material for a Sustainable Tissue Replacement Bank
Silicone-aided Advanced Additive Manufacturing of Glass and Glass-ceramic Scaffolds
Targeting Cancer-associated Fibroblasts within a Tumor Microenvironment via Liposomes with Arginine-based Surface Modifiers
Wear Particle-induced Differentially Polarized Macrophages Exhibit Variation in Protein Profile than M1 and M2

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