Bi2Te3-based p-type Bi0.5Sb1.5Te3 and n-type Bi2Te2.7Se3 have been the only materials used for thermoelectric cooling for more than five decades. Even though the progress on advancing the thermoelectric figure-of-merit (ZT) has been significant especially the materials with peak ZT at high temperatures, materials with high ZT around room temperature are very rare. Up to now, besides Bi2Te3-based ones, the only reported is p-type MgAgSb with ZT of ~0.8 at room temperature. There is no report on any n-type material exhibiting high ZT at around room temperature. In this talk, I will present a new n-type material that has a ZT of ~0.7 at room temperature, and the cooling performance coupled with p-type Bi0.5Sb1.5Te3, and also power generation performance coupled with either p-type Bi0.5Sb1.5Te3 or p-type MgAgSb.