| About this Abstract |
| Meeting |
MS&T22: Materials Science & Technology
|
| Symposium
|
Society for Biomaterials: Biomaterial Applications in Today’s Industry: Development, Translation & Commercialization
|
| Presentation Title |
Optimized Nanopatterned Electrodes for Enhanced Electrochemical Biosensors |
| Author(s) |
Emily R. Kinser |
| On-Site Speaker (Planned) |
Emily R. Kinser |
| Abstract Scope |
The benefits of nanotopography as a means of performance enhancement have been demonstrated across multiple biosensing methodologies and materials sets. To expand the potential applications of nanopatterned biosensors, biocompatible nanopatterned structures which are highly uniform and reliable are required. An optimized nanopatterned electrode structure consisting of nanorods with a gold core combined with an active platinum surface layer was created, which enabled demonstration of electrochemical sensing of glucose with increased signal and sensitivity. Arrays of nanorods with varying pitch were also fabricated in order to study the influence of nanorod pitch on biosensor performance. Additionally, interaction of fibroblast cells with the nanopatterned substrates with varying nanorod pitch was assessed utilizing FIB-SEM microscopy. With manufacturability as a key consideration, the nanopatterned electrodes were fabricated utilizing established commercial semiconductor-compatible processes to create a biosensor technology that is both novel and scalable. |