|About this Abstract
|MS&T21: Materials Science & Technology
|Additive Manufacturing of Ceramic-based Materials: Process Development, Materials, Process Optimization and Applications
|Multifunctional Artificial Artery from Direct 3D Printing with Built-in Ferroelectricity and Tissue-Matching Modulus
|On-Site Speaker (Planned)
In this work, electric field-assisted 3D printing technology was developed to fabricate in situ-poled ferroelectric artificial arteries that offered battery-free real-time blood pressure sensing and occlusion monitoring capability. The functional artery architecture was made by the development of a printable ferroelectric bio-composite that could be quickly polarized during printing and reshaped into devised objects. Synergistic effect from the ferroelectric potassium sodium niobate (KNN) particles and the ferroelectric polyvinylidene fluoride (PVDF) polymer matrix yielded a superb piezoelectric performance (d33 > 12 pC N-1, confirmed by piezometer) on a par with that of commercial ferroelectric polymers. The sinusoidal architecture brought the mechanical modulus down to the same level of human blood vessels. The 3D-printed artificial artery provided an excellent sensitivity to pressure change (0.306 mV/mmHg, R2> 0.99) within the range of human blood pressure. The ability to detect subtle vessel motion change enabled early detection of thrombosis, allowing for preventing grafts failure.