| About this Abstract |
| Meeting |
2025 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advances in Surface Engineering VII
|
| Presentation Title |
Cleanability Testing of Fluoropolymer Linings to Combat Corrosion in Pharmaceutical Applications |
| Author(s) |
Lucas Bolster, Drew Klaus, George Fisher, Taylor Sparks |
| On-Site Speaker (Planned) |
Lucas Bolster |
| Abstract Scope |
Electropolished stainless steel (EP SS) has been standard for storage of pharmaceutical buffers and solutions for some time due to its smoothness and great cleanability. However, EP SS is prone to corrosion and contamination, so we propose the use of various fluoropolymer coatings to combat this issue. While EP SS is smoother than nearly all fluoropolymer coatings, we believe polytetrafluoroethylene (PTFE), Polyvinylidene fluoride (PVDF), and ethylene tetrafluoroethylene (ETFE) can perform similarly to EP SS in cleanability testing while solving the problem of corrosion and contamination. Characterization of the coatings and EP SS is done with a solution containing uranine as a fluorescent tracer and a standardized soiling and cleaning technique. Fluorescence of residual uranine is measured in all samples with a fluorometer and compared with surface roughness and surface profile data collected with a profilometer. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Surface Modification and Coatings, Polymers, Characterization |